Browsing by Author "Reyes Parada, Miguel"
Now showing items 1-20 of 24
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(Springer, 1996)Serotonergic behavioral responses, efTects on motor activity and core temperature, and binding properties of the novel putative anxiolytic amphe!amine derivative (± )1-(2,5-dimethoxy-4-ethylthlophenyl)- 2-aminopropane ...
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(ELSEVIER, 2010)2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided ...
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(2010)2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
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(EIsevier Science Ltd., 1994-04-04)4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
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(Elsevier , Science Ltd., 1994-04-04)4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
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(2012)4-Methylthioamphetamine (MTA) is a phenylisopropylamine derivative whose use has been associated with severe intoxications. MTA is usually regarded as a selective serotonin-releasing agent. Nevertheless, previous data have ...
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(Elsevier Science Inc., 2000-06-06)To assess the pharmacodynamic profile of ALEPH-2, a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties, Xenopus laevis oocytes were microinjected with either of the rat cRNA for the ...
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(Elsevier Science Inc., 1998-07-07)The dopaminergic and antioxidant properties of pukateine [(R)-11-hydroxy-1,2-methylenedioxyaporphine, PUK], a natural aporphine derivative, were analyzed in the rat central nervous system. At dopamine (DA) D1 ([3H]-SCH ...
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(Oxford University Press, 2019)© The Author(s) 2018.Studies in rats have shown that a decrease in either protein content or total dietary calories results in molecular, structural, and functional changes in the cerebral cortex and hippocampus, among ...
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(2007)2,5-Dimethoxy-4-substituted phenylisopropylamines and phenethylamines are 5-hydroxytryptamine (serotonin) (5-HT)(2A/2C) agonists. The former are partial to full agonists, whereas the latter are partial to weak agonists. ...
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(The American Society for Pharmacology and Experimental Therapeutics, 2007-02-28)2,5-Dimethoxy-4-substituted phenylisopropylamines and phenethylamines are 5-hydroxytryptamine (serotonin) (5-HT)2A/2C agonists. The former are partial to full agonists, whereas the latter are partial to weak agonists. ...
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(Elsevier Ltd., 2007-05-22)Abstract—Four enantiomerically pure (S)-4-alkylthioamphetamine derivatives were evaluated as monoamine oxidase (MAO) inhibitors using the human and rat isoforms of the enzyme. Molecular dockings were performed in order ...
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(Nordic Pharmacological Society), 2014)Abstract: Amphetamine derivatives have therapeutic potential in diseases such as attention deficit hyperactivity disorder, narcolepsy and obesity. However, their prolonged use has been associated with cardiovascular ...
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(Bentham Science Publishers Ltd., 2004-11-25)The recent description of the crystal structures of rat MAO-A and human MAO-B provides an unprecedented framework to elucidate the mechanisms underlying the selective interactions between these proteins and their ligands. ...
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(Elsevier Science Ltd., 1993-11-13)The in vitra and ex viva monoamine oxidase (MAO) inhibitory effects of (±)4-dimethylaminoa- methyl-phenethylamine (4-DMAA) and (± )4-methylamino-a-methyl-phenethylamine (4-MAA) were reassessed, in comparison with the ...
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(1994)The in vitro and ex vivo monoamine oxidase (MAO) inhibitory effects of (±)4-dimethylamino-α-methyl-phenethylamine 4-DMAA) and (±)4-methylamino-α-methyl-phenethylamine (4-MAA) were reassessed, in comparison with the previously ...
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(Taylor & Francis Ltd, 2003-03-10)(6)-4-Methylthioamphetamine (MTA) was resolved into its enantiomers, and a series of N-alkyl derivatives of the parent compound, as well as its a-ethyl analogue, were prepared. The monoamine oxidase (MAO) inhibitory properties ...
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(1997)The monoamine oxidase (MAO) inhibitory properties of a series of amphetamine derivatives with different substituents at or around the para position of the aromatic ring were evaluated. In in vitro studies in which a crude ...
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(Elsevier Ltd., 2009-02-08)A series of naphthylisopropylamine and N-benzyl-4-methylthioamphetamine derivatives were evaluated as monoamine oxidase inhibitors. Their potencies were compared with those of a series of amphetamine derivatives, to test ...
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(Universidad de Chile, 2001)
